Isoquinoline 97 Percent Pure Research Grade

Product Identification & Chemical Properties Summary

High-Purity Isoquinoline (2-Azanaphthalene) Supply

We manufacture and supply high-purity Isoquinoline (CAS 119-65-3), a foundational fused heterocyclic aromatic compound consisting of a benzene ring fused to a pyridine ring at positions 3 and 4. As the structural isomer of quinoline, this versatile 2-azanaphthalene core serves as a critical organic synthesis intermediate for modern pharmaceutical manufacturing, crop protection chemicals, and advanced material science applications.

Essential Identifiers & Chemical Data

Parameter	Technical Specification
Product Name	Isoquinoline
CAS Registry Number	119-65-3
Chemical Formula	C9H7N
Molecular Weight	129.16 g/mol
IUPAC Name	Isoquinoline
Synonyms	2-Azanaphthalene, Benzo[c]pyridine, Leucoline
Purity Grade	≥98.0% (Standard Synthesis) / ≥99.0% (Custom High-Purity)
SMILES Structure	c1ccc2cnccc2c1

Technical Specifications & Physical Constants

We supply high-purity Isoquinoline (CAS 119-65-3) engineered for demanding synthesis pipelines. Known as 2-azanaphthalene, our product maintains precise physical constants to guarantee reproducible organic reactions and predictable commercial yields.

Isoquinoline Physical Parameters

Physical Parameter	Specification / Value
CAS Registry Number	119-65-3
Chemical Name	Isoquinoline (2-azanaphthalene)
Melting Point	23–28°C
Boiling Point	242–243°C
Density	1.099 g/mL (at 25°C)
Refractive Index	1.622–1.625 ($n_{20}/D$)
Flash Point	107°C
Basicity (pKa)	5.14
Solubility	Slightly soluble in water; freely soluble in ethanol, ether, and diluted acids

Batch Consistency Guarantee

Downstream processing relies on zero batch variation. We enforce strict chromatographic testing protocol on every production lot to eliminate structural isomers and unwanted impurities:

• High-Resolution GC & HPLC Testing: We analyze every batch via Gas Chromatography and HPLC to ensure strict compliance with purity limits.
• Yield & Reaction Stability: By eliminating non-volatile residues and trace organic contaminants, we help you avoid catalyst poisoning and maintain predictable reaction kinetics.
• Moisture Protection: Low baseline water content guarantees stable performance during moisture-sensitive functional group transformations at positions 1 and 5.

Industrial Applications & Reaction Pathways of Isoquinoline

We manufacture high-purity Isoquinoline (CAS 119-65-3) to serve as a versatile 2-azanaphthalene building block across commercial synthesis pipelines. Its distinct bicyclic structure allows for reliable functionalization, making it an essential intermediate for pharmaceuticals, agrochemicals, and fine chemistry.

Pharmaceutical Intermediates & Alkaloid Synthesis

Our Isoquinoline provides the key core scaffold for complex active pharmaceutical ingredients (APIs) and synthetic alkaloids:

• Alkaloid Derivatives: Core feedstock for synthesizing papaverine, berberine, and various morphine-like compounds.
• Therapeutics: Essential foundation for modern muscle relaxants, antihypertensive agents, and cardiovascular treatments.
• Antimicrobial Agents: Crucial intermediate for novel broad-spectrum antibacterial and antifungal drug platforms.

Agrochemical & Crop Protection Solutions

We supply high-grade Isoquinoline to meet the strict purity demands of agricultural chemistry:

• Fungicides & Herbicides: Key precursor for active crop protection compounds targeting resistant plant pathogens.
• Yield Protection: Used in formulating synthetic crop preservers and growth-regulating agents.

Specialty Dyes, Catalysts & Organic Electronics

Isoquinoline’s conjugated aromatic framework makes it ideal for advanced material manufacturing:

• Fluorescent Dyes: Essential intermediate for producing high-intensity optical brighteners and industrial markers.
• Organometallic Catalysts: Functions as an effective nitrogen-donor ligand in metal-catalyzed organic transformations.
• Organic Electronics: Precursor material for specialized OLED formulations and organic semiconductor research.

Reaction Pathways & Custom Functionalization

We deliver high-purity material that ensures clean, predictable reaction pathways during downstream processing:

Reaction Type	Target Position	Synthetic Outcome
Electrophilic Substitution	Positions 5 & 8	High-yield nitration and sulfonation under controlled acid conditions
Nucleophilic Addition	Position 1	Efficient C-1 amination (Chichibabin reaction), alkylation, and acylation
Selective Hydrogenation	Pyridine Ring	Catalytic reduction to 1,2,3,4-tetrahydroisoquinoline scaffolds

Quality Assurance, Safety & Regulatory Documentation for Isoquinoline

Greenlano Quality Control Protocol

We guarantee the purity and yield stability of our Isoquinoline (CAS 119-65-3) through direct, rigorous quality checks at our facility. Every batch undergoes full testing to ensure seamless performance in downstream organic synthesis and manufacturing.

• 100% Batch Analytical Testing: Every production lot of Isoquinoline is verified using Gas Chromatography (GC) and High-Performance Liquid Chromatography (HPLC) to guarantee pure assay levels and clear impurity profiles.
• Third-Party Inspection Options: To meet strict global compliance standards, we provide optional SGS or Bureau Veritas (BV) pre-shipment inspections upon request.

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Isoquinoline Safety & Regulatory Profile

Proper handling and regulatory compliance are essential when importing 2-Azanaphthalene. We maintain complete GHS and shipping data to protect your operational timeline and facility personnel.

Parameter	Standard Classification & Profile
GHS Signal Word	Danger
Hazard Classes	Acute Toxicity (Oral, Dermal), Skin Irritation (Category 2), Eye Irritation (Category 2A)
UN Transport Number	UN 2811
Shipping Class & PG	Class 6.1 (Toxic Substances), Packing Group III
Hazard Statements	Toxic in contact with skin (H311), Harmful if swallowed (H302), Causes skin and eye irritation (H315, H319)

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Downloadable Technical Resources

We streamline your procurement and compliance audits by providing immediate access to updated technical literature for every Isoquinoline order:

• Safety Data Sheet (SDS/MSDS): Fully compliant GHS-formatted safety sheets covering toxicity, storage safety, and emergency protocols.
• Certificate of Analysis (COA): Lot-specific analytical reports detailing exact GC purity percentages and physical metrics.
• Technical Data Sheet (TDS): Full structural properties, chemical specs, and handling recommendations.

Packaging, Storage & Global Logistics Solutions for Isoquinoline

We manage the end-to-end supply chain for Isoquinoline, ensuring your product arrives on time, fully certified, and chemically pristine. Whether you need small quantities for R&D or bulk supply for commercial manufacturing, we tailor our packaging, storage, and transport protocols to fit your operation.

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Flexible Isoquinoline Packaging Options

We provide secure container configurations for Isoquinoline (CAS 119-65-3) engineered to preserve purity and prevent leakage during international transit:

Supply Scale	Packaging Type	Target Application
R&D & Lab Scale	1 kg / 5 kg HDPE bottles & sealed glass containers	Analytical testing, formulation trials
Pilot Scale	25 kg steel drums with double PE liners	Intermediate batch synthesis
Industrial Commercial	200 kg iron drums & 1,000 kg IBC Totes	Large-scale chemical production

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Recommended Storage Conditions for 2-Azanaphthalene

Isoquinoline (also known as 2-azanaphthalene) can discolor or absorb atmospheric moisture if handled improperly. To maintain target purity and yield stability, we recommend the following warehouse handling protocols:

• Inert Blanketing: Store material sealed under a dry nitrogen blanket to minimize exposure to air and ambient moisture.
• Temperature Control: Keep containers in a cool, dry, well-ventilated area away from direct sunlight and heat sources.
• Container Seal Integrity: Keep drums tightly closed when not in active use to prevent light-induced oxidation and moisture uptake.

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Global Shipping & Hazmat Compliance

Shipping liquid heterocycles across international borders requires strict regulatory compliance. We streamline export procedures to guarantee uninterrupted port entry and drop-off at your site.

• Hazmat-Certified Packing: Fully certified for IMDG (Sea Freight) and IATA (Air Freight) dangerous goods transport with UN-approved heavy-duty drums.
• Complete Customs Clearance Support: We handle all export documentation, including tailored Harmonized System (HS) code filings, Dangerous Goods Declarations, SDS/MSDS, and Certificates of Analysis (COA).
• Global Logistics Network: Direct freight channels cover major ports in North America, Europe, Asia-Pacific, and Latin America with real-time consignment tracking.

Why Source Isoquinoline from Greenlano Chemical?

We supply high-grade isoquinoline directly from our synthesis facilities, giving you complete control over your procurement costs, product purity, and delivery timelines. By eliminating intermediary trading markups, we deliver direct-factory value paired with strict quality controls to protect your chemical manufacturing pipelines.

Core Supply Advantages

• Direct Factory Pricing: Eliminate broker margins and secure competitive rates straight from our production floor.
• Uncompromising Yield Consistency: Strict manufacturing controls minimize batch-to-batch variation, ensuring reliable downstream synthesis yields.
• Rapid RFQ Turnaround: Receive official commercial quotes, COAs, and technical support within 2 to 24 hours.
• Custom Supply Chain Programs: Access flexible MOQs, vendor-managed inventory (VMI), and customized packaging or private labeling solutions.

Greenlano Supply Capabilities

Parameter	Greenlano Standard	Customer Benefit
Sourcing Model	Direct manufacturer supply	Lower procurement costs with no broker fees
Batch Control	Process automation & GC/HPLC testing	Predictable reaction behavior and high yield stability
Commercial Execution	2 to 24-hour RFQ response	Faster purchasing cycles and project timelines
Logistics Support	Tailored MOQs, VMI & private labeling	Streamlined inventory management and lower storage overhead

We deliver reliable isoquinoline supply with transparent pricing, full regulatory compliance, and fast turnarounds for your global operational needs.

Frequently Asked Questions

Here are direct answers to common technical and commercial queries regarding our Isoquinoline (CAS 119-65-3 / 2-azanaphthalene) supply.

Standard Purity and Custom Options

• Standard Grade: We supply Isoquinoline with a minimum purity of ≥98.0% verified by Gas Chromatography (GC).
• Custom Grades: We manufacture custom high-purity (≥99.5%) and low-moisture grades to fit specialized downstream synthesis requirements.

Transit Moisture Protection

• Atmospheric Protection: Every container is packed under an inert nitrogen blanket and sealed airtight.
• Container Integrity: Heavy-duty steel drums, iron drums, and UN-rated IBC totes prevent moisture absorption and ambient oxidation during global transport.

EU REACH & Import Compliance

Compliance Standard	Support Provided
EU REACH	Full registration documentation and REACH-compliant SDS for seamless European import clearance.
Batch Documentation	Complete Certificate of Analysis (COA) and Technical Data Sheet (TDS) shipped with every order.

Order Lead Times & Sample Requests

• Analytical Samples: We offer lab-scale testing quantities (100 g to 1 kg) alongside a full COA prior to commercial commitments.
• Delivery Timelines: Standard in-stock orders ship within 3 to 5 business days. Commercial bulk orders average 2 to 3 weeks.