What is O-Vanillin? Chemical Properties and Structure
O-Vanillin, also known as Ortho-Vanillin or 2-Hydroxy-3-methoxybenzaldehyde, is a versatile organic compound widely recognized for its strong aromatic profile and reactive functional groups. Chemically, it is an isomer of vanillin, distinguished by the position of its hydroxyl and methoxy groups on the benzaldehyde ring.
- Molecular formula: C8H8O3
- Molecular weight: 152.15 g/mol
Key Functional Groups:
- Aldehyde group (-CHO): Responsible for its reactivity in synthesis and biochemical applications.
- Phenol group (-OH): Contributes to its antioxidant properties and influences solubility.
- Ether group (-OCH3): Adds to its chemical stability and unique molecular behavior.
Physical Characteristics:
- Appearance: Pale yellow crystalline powder
- Melting point: Approximately 45–50°C
- Solubility: Soluble in organic solvents like ethanol and DMSO; sparingly soluble in water
O-Vanillin’s combination of aromatic structure and reactive groups makes it a crucial intermediate in pharmaceuticals, antifungal agents, and biochemical research.
Key Specifications and Technical Data of O-Vanillin
Here’s a quick rundown of the key specs for O-Vanillin (also known as Ortho-Vanillin or 2-Hydroxy-3-methoxybenzaldehyde), so you know exactly what you’re getting:
| Specification | Details |
|---|---|
| Purity | ≥ 98% (Lab-grade / Analytical quality) |
| CAS Number | 148-53-8 |
| Synonyms | Ortho-Vanillin, 3-Methoxysalicylaldehyde |
| Molecular Weight | 152.15 g/mol |
| Appearance | Pale yellow to light brown crystalline powder |
| Solubility | Soluble in ethanol, ether, and chloroform; slightly soluble in water |
| Storage Conditions | Store in a cool, dry place; keep container tightly closed away from light |
| Packaging Options | Available in 10g, 100g, 500g, 1kg, and 2.5kg packs |
Our O-Vanillin meets strict quality controls and is packaged for safe transport worldwide, fitting the needs of labs and industries alike.
Applications of O-Vanillin in Research and Industry
O-Vanillin (also known as Ortho-Vanillin or 2-Hydroxy-3-methoxybenzaldehyde) is widely used across various fields due to its versatile properties.
Pharmaceutical Precursor
It serves as a key building block in synthesizing drugs like benafentrine and several antiandrogens. These compounds are important in treating conditions such as asthma and hormone-related disorders.
Antifungal and Antimicrobial Uses
O-Vanillin is effective against fungi like Aspergillus flavus. It works by disrupting the fungal cell wall, making it a valuable antifungal benzaldehyde derivative in agricultural and medical research.
Biochemical and Toxicity Studies
In lab settings, O-Vanillin is used to study NF-κB inhibition—an essential pathway in inflammation and cancer research. It also features in DNA damage assays, helping researchers understand genetic toxicity and repair mechanisms.
Emerging Roles
Recent studies highlight O-Vanillin’s potential as a free radical scavenger, protecting cells from oxidative stress. It also shows promise in modulating microglial phenotypes, a key factor in treating neuroinflammatory diseases.
With these diverse applications, O-Vanillin is a reliable organic aldehyde intermediate for both industrial and research purposes worldwide.
Why Choose Gotrays O-Vanillin?
When it comes to O-Vanillin, quality and reliability are key. Here’s why Gotrays stands out as your go-to supplier:
Unmatched Purity and Compliance
- ISO 9001 Certified: Ensures consistent high-quality standards.
- REACH & TSCA Registered: Fully compliant with global chemical safety regulations.
- High Purity Grade: Lab-grade O-Vanillin with minimal impurities for precise research and industrial applications.
Flexible Packaging and Fast Global Shipping
| Package Size | Availability | Delivery Time |
|---|---|---|
| 10g | Ready stock | 1-3 business days |
| 100g | Ready stock | 1-3 business days |
| 500g | Made to order | 2-5 business days |
| 2.5kg | Made to order | 3-7 business days |
- Ships worldwide with secure packaging tailored to your needs.
- Quantity options fit small labs to large-scale manufacturing.
Expert Support at Your Fingertips
- Dedicated chemists available for technical questions and custom orders.
- Reliable customer service helps you select the right grade and quantity for your project.
- Tailored advice for formulations, storage, and handling.
Choosing Gotrays O-Vanillin means you get more than just a chemical—you get a trusted partner for your research and production needs.
Safety, Handling, and Regulatory Information
Hazard Overview
O-Vanillin (CAS 148-53-8) can cause irritation to the skin, eyes, and respiratory tract. It’s important to handle it carefully to avoid contact. The LD50 (oral, rat) is moderate, so ingestion should be strictly avoided. Always treat O-Vanillin as a chemical irritant during use.
Best Practices for Handling
- Storage: Keep O-Vanillin in a cool, dry place, tightly sealed to prevent moisture exposure. Avoid direct sunlight.
- Personal Protective Equipment (PPE): Always wear gloves, safety goggles, and lab coats when handling. Use respiratory protection if dust or vapor exposure is possible.
- Spill Response: Clean spills promptly with appropriate absorbents and ventilate the area well.
Environmental Impact
Our O-Vanillin is produced through sustainable synthesis processes that minimize waste and energy use. We follow REACH and TSCA guidelines to ensure environmental safety. Proper disposal methods are recommended to prevent ecological harm.
By following these safety and handling guidelines, you can work confidently with O-Vanillin while ensuring compliance and protecting health and the environment.
Pricing, Availability, and Bulk Orders
We offer competitive pricing on O-Vanillin, with a dynamic pricing table that adjusts based on order size. The more you buy, the better the discount—perfect for labs or industries needing larger quantities.
- Tiered Discounts: Save more when ordering in bulk (from 10g up to 2.5kg).
- Flexible Quantities: Easily select your desired amount with our simple quantity selector.
- Fast Checkout: Add to cart with just a few clicks, ready for quick processing.
FAQs on Ordering and Payment
- What’s the difference between product grades? We provide lab-grade O-Vanillin with consistent purity, ideal for research and industrial use.
- Which payment methods are accepted? We accept major credit cards, PayPal, and bank transfers for international customers.
- Is international shipping available? Yes, with reliable delivery options tailored to your location and order size.
For any questions on pricing or bulk orders, our customer support team is ready to help you find the best solution.
Frequently Asked Questions (FAQ)
Is O-Vanillin suitable for food-grade applications?
O-Vanillin (also known as Ortho-Vanillin or 2-Hydroxy-3-methoxybenzaldehyde) is primarily designed for research and industrial use. It’s not certified for food-grade or direct food applications. If you need a food-safe product, we recommend checking regulatory compliance and opting for food-grade vanillin variants.
What is the usual lead time for international orders?
We ship globally with delivery typically within 1–3 business days for standard orders. For international shipments, the lead time can vary depending on customs and local logistics but generally falls between 3 to 7 days. Expedited options and bulk orders may require customized delivery scheduling.
Where can I find more information or resources on O-Vanillin?
We offer several related blog articles and detailed guides to help you understand O-Vanillin better. These cover topics such as its role as a pharmaceutical precursor, its antifungal activities, and emerging research on free radical scavenging. Feel free to explore our resource center or subscribe to our newsletter for the latest updates.
How can I contact support for technical or custom inquiries?
Our dedicated team of chemists is ready to assist with any product questions or special requirements. Reach out through our website or support email for fast, expert help tailored to your project.
Related Products and Resources
Looking for products similar to O-Vanillin? Check out our product carousel featuring related aldehydes like salicylaldehyde analogs and other methoxybenzaldehyde derivatives. These compounds are great for various research and industrial applications.
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