Sodium Difluoroacetate Specifications and Properties
Chemical Identity and Physical Data for CAS 2218-52-2
At Gotrays, we specialize in the direct manufacturing and global supply of high-purity Acetic acid, 2,2-difluoro-, sodium salt(1:1). Commonly utilized as a robust difluoromethylation reagent, this organofluorine intermediate is critical for introducing fluorine moieties into complex pharmaceutical and agrochemical structures. We ensure our Sodium difluoroacetate maintains strict structural integrity and chemical stability, appearing typically as a white to off-white crystalline solid.
Our production line guarantees consistent specifications, eliminating the variability often found with secondary distributors. Below are the key technical parameters for our Sodium 2,2-difluoroacetate:
| Property | Specification |
|---|---|
| Product Name | Acetic acid, 2,2-difluoro-, sodium salt(1:1) |
| CAS Number | 2218-52-2 |
| Synonyms | Difluoroacetic acid sodium salt, Sodium 2,2-difluoroacetate |
| Molecular Formula | C2HF2NaO2 |
| Molecular Weight | 118.04 g/mol |
| Appearance | White to off-white powder/crystal |
| Purity | ≥98% (HPLC) |
| Solubility | Soluble in water and polar organic solvents |
As a reliable Sodium difluoroacetate supplier, we prioritize transparency in our technical data. The compound features a stable C2HF2NaO2 structure, making it an ideal fluorinated building block for research and industrial scaling. We provide comprehensive documentation, including COA and Sodium difluoroacetate MSDS, to support your procurement and compliance requirements.
Primary Applications in Organic Synthesis
Using Sodium 2,2-difluoroacetate as a Difluoromethylation Reagent
We supply Acetic acid, 2,2-difluoro-, sodium salt(1:1) primarily as a versatile tool for synthetic chemists. In the world of organofluorine intermediates, this compound serves as a critical difluoromethylation reagent. Its ability to introduce the difluoromethyl (CF2H) group into organic molecules makes it indispensable for modifying the properties of bioactive compounds.
For researchers and manufacturers, Sodium 2,2-difluoroacetate acts as a reliable difluorocarbene precursor. By generating difluorocarbene in situ, it facilitates reactions that are otherwise difficult to achieve. This makes it a top choice when developing advanced fluorinated building blocks for new drugs or materials.
Key Applications Include:
- Pharmaceutical Synthesis: Used as one of the essential pharmaceutical fluorination agents to enhance metabolic stability and lipophilicity in drug candidates.
- Agrochemical Development: A vital raw material for creating potent herbicides and pesticides.
- Material Science: Employed in the production of specialized polymers and fluorinated materials.
- Custom Synthesis: We support R&D teams using this salt to create complex molecular structures through direct difluoromethylation.
Quality Control and Purity Standards
We know that consistency is everything when you are running complex reactions. That is why we enforce strict quality protocols for our Acetic acid, 2,2-difluoro-, sodium salt(1:1). As a direct factory supplier, we oversee the entire manufacturing process to ensure you get reliable Sodium difluoroacetate every time, eliminating the risks associated with inconsistent organofluorine intermediates.
Guaranteed Specifications
We don’t just guess; we verify. Our professional R&D team uses advanced HPLC analysis to confirm that every batch meets our high standards before it leaves the warehouse. Whether you are sourcing fluorinated building blocks for lab research or commercial production, we back our products with tangible data.
- Purity Assurance: We guarantee a minimum purity of ≥98%, with many production runs typically reaching ≥99%.
- Documentation: Full transparency is standard. We provide a Certificate of Analysis (COA) and Sodium difluoroacetate MSDS (SDS) upon request.
- Batch Consistency: Our controlled manufacturing environment ensures uniform quality, providing stability for your pharmaceutical fluorination agents.
Safety, Handling, and Storage Protocols
We prioritize safety and product integrity when supplying Acetic acid, 2,2-difluoro-, sodium salt(1:1). Before integrating this chemical into your workflow, it is essential to review the Sodium difluoroacetate MSDS to understand specific hazard codes and emergency procedures. While we ensure rigorous quality control at the factory level, maintaining that quality requires proper management at your facility.
To ensure stability and safety, follow these key guidelines:
- Personal Protective Equipment (PPE): Always wear safety glasses, chemical-resistant gloves, and a lab coat. If dust formation is likely, use appropriate respiratory protection to avoid inhalation of this difluoromethylation reagent.
- Optimal Storage Conditions: Store CAS 2218-52-2 in a cool, dry, and well-ventilated place. The container must be kept tightly closed to prevent moisture absorption, which can affect the performance of fluorinated building blocks.
- Handling Precautions: Avoid contact with skin and eyes. Keep the product away from incompatible materials, such as strong oxidizing agents, to prevent unwanted reactions and ensure the longevity of your organofluorine intermediates.
Packaging Options and Global Logistics for Sodium Difluoroacetate
At Gotrays chemical supply, we understand that project needs vary from the benchtop to the manufacturing floor. We offer flexible packaging solutions for Acetic acid, 2,2-difluoro-, sodium salt(1:1) to match your specific scale of operation. Whether you need a few grams for R&D or metric tons for commercial production, we ensure your material arrives safely and securely.
We prioritize product integrity during transit. For bulk orders of Sodium 2,2-difluoroacetate, we utilize robust, UN-rated fiber drums lined with double polyethylene bags to prevent moisture absorption and contamination.
Standard Packaging Configurations
| Scale | Package Type | Typical Quantity |
|---|---|---|
| Lab / R&D | Glass Vials / HDPE Bottles | 25g, 100g, 500g |
| Pilot Plant | Aluminum Foil Bags / Plastic Drums | 1kg, 5kg, 10kg |
| Commercial | Fiber Drums (UN-Rated) | 25kg, 50kg |
Global Shipping and Compliance
Shipping chemical intermediates like CAS 2218-52-2 requires strict adherence to international regulations. Our logistics team manages the entire process:
- Fast Dispatch: We keep stock ready for immediate shipment to minimize lead times.
- Documentation: Full MSDS and COA provided for smooth customs clearance.
- Safety: Specialized packing materials used to maintain stability during air or sea freight.
We deliver Sodium difluoroacetate globally, ensuring that your supply chain remains uninterrupted regardless of your location.
FAQ: Common Questions About Sodium Difluoroacetate
We understand that sourcing Acetic acid, 2,2-difluoro-, sodium salt(1:1) involves strict technical and logistical requirements. As a dedicated partner in Gotrays chemical supply, we prioritize transparency and efficiency to support your production goals. Here are the answers to the most frequent inquiries regarding CAS 2218-52-2.
Technical & Logistics Support
- Solubility & Stability: Sodium difluoroacetate is typically soluble in water and polar organic solvents. To maintain the stability of this difluoromethylation reagent, it must be stored in a cool, dry, and well-ventilated environment, tightly sealed to prevent moisture absorption.
- Documentation Availability: Quality assurance is our standard. We provide a full Certificate of Analysis (COA) and Sodium difluoroacetate MSDS with every shipment, ensuring you have the necessary safety and specification data for compliance.
- Shipping & Lead Times: As a direct Sodium difluoroacetate supplier, we offer competitive factory prices and rapid dispatch. Whether you need research-grade vials or bulk drums of fluorinated building blocks, our global logistics network ensures safe and timely delivery.
- Custom Synthesis: If your project requires specific purity adjustments or unique packaging for 2,2-Difluoroacetic acid sodium salt, our professional R&D team is available to discuss custom solutions.


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