Product Overview of 2-Chlorobenzonitrile
What is 2-Chlorobenzonitrile?
2-Chlorobenzonitrile, also known as o-Chlorobenzonitrile or 2-Cyanophenyl chloride, is a crucial chemical intermediate widely used in various industries. It is an aromatic compound featuring a chlorine atom and a nitrile group attached to a benzene ring at the ortho position.
Basic Identification
- Chemical Name: 2-Chlorobenzonitrile
- CAS Number: 121-96-0
- Synonyms: o-Chlorobenzonitrile, 2-Cyanophenyl chloride, ortho-chlorobenzonitrile
Key Selling Points
- High Purity: Available in high-purity grades suitable for sensitive applications in pharmaceuticals and agrochemicals.
- Reliable Intermediate: Essential building block for synthesizing fine chemicals, specialty compounds, and active pharmaceutical ingredients (APIs).
- Consistent Quality: Manufactured under strict quality controls to ensure batch-to-batch consistency.
- Versatile Use: Broad application scope across multiple industries including R&D, making it a preferred choice for chemical manufacturers.
- Regulatory Compliance: Supplied with up-to-date safety documentation, including Safety Data Sheets (SDS) and REACH compliance certificates.
This combination of purity, quality assurance, and versatility makes 2-Chlorobenzonitrile a dependable choice for industrial and research needs worldwide.
Chemical Identity & Structure of 2-Chlorobenzonitrile
2-Chlorobenzonitrile, also known as o-Chlorobenzonitrile or 2-Cyanophenyl chloride, is an aromatic organic compound. Its chemical formula is C7H4ClN, where a chlorine atom is attached to the ortho position of the benzene ring relative to the nitrile group (–CN). This specific positioning distinguishes it from other isomers like 3-chlorobenzonitrile (meta) and 4-chlorobenzonitrile (para).
Nomenclature and Related Compounds
- IUPAC Name: 2-Chlorobenzonitrile
- Common Names: o-Chlorobenzonitrile, 2-Cyanophenyl chloride, Ortho-chlorobenzonitrile
- CAS Number: [Not specified here, but commonly referenced in data]
Structural Information
- The molecule features a benzene ring with two substituents:
- A nitrile group at carbon 1
- A chlorine atom at carbon 2 (ortho position)
- This arrangement imparts specific chemical reactivity, making it particularly useful in synthesis as an intermediate.
Isomers and Related Compounds
- 3-Chlorobenzonitrile (meta position)
- 4-Chlorobenzonitrile (para position)
- Other halogenated benzonitriles like 2-bromobenzonitrile, which share similar applications but differ in reactivity.
This chemical identity provides a clear basis for understanding how 2-Chlorobenzonitrile behaves and interacts with other substances, essential for its role as a pharmaceutical and agrochemical intermediate.
Physicochemical Properties of 2-Chlorobenzonitrile
Physical Description
2-Chlorobenzonitrile is a colorless to pale yellow crystalline solid. It usually appears as a fine powder or small granules. It has a distinct sharp odor typical of nitrile compounds.
Key Properties
- Molecular formula: C7H4ClN
- Molecular weight: 137.56 g/mol
- Melting point: Approximately 38-41°C
- Boiling point: Around 215-217°C
- Density: About 1.31 g/cm³
- Solubility: Moderately soluble in common organic solvents like ethanol, benzene, and acetone; low solubility in water
- Appearance: Solid at room temperature with good chemical stability
Stability & Reactivity Profile
- Chemical stability: Stable under normal storage conditions. It resists hydrolysis and oxidation when kept dry and away from strong acids or bases.
- Reactivity: Reacts predictably in electrophilic aromatic substitution and nucleophilic substitution reactions due to the nitrile group and the chlorine substituent at the ortho position.
- Handling caution: Avoid contact with strong oxidizers, bases, and prolonged exposure to moisture to maintain product integrity.
- Shelf life: Maintains stability for long periods when stored properly in sealed containers, away from direct sunlight and extreme temperatures.
This balance of stability and reactivity makes 2-Chlorobenzonitrile a reliable intermediate for various chemical syntheses in pharmaceuticals and agrochemicals.
Quality Specifications & Analytical Data for 2-Chlorobenzonitrile
Standard Specification (Gotrays Grade)
Gotrays offers high-purity 2-Chlorobenzonitrile that meets strict quality criteria, ensuring reliability for your synthesis needs. Here’s an overview of the standard specification:
| Parameter | Specification |
|---|---|
| Purity (GC) | ≥ 99.0% |
| Appearance | Colourless to pale yellow liquid or solid |
| Boiling Point | ~205°C |
| Moisture (KF) | ≤ 0.2% |
| Assay | ≥ 99.0% |
| Residue on ignition | ≤ 0.05% |
Analytical Methods
Gotrays uses advanced and reliable analytical techniques to guarantee the quality of 2-Chlorobenzonitrile:
- Gas Chromatography (GC) for purity and assay
- Karl Fischer Titration for moisture determination
- NMR & IR Spectroscopy to confirm structural integrity
- Melting / Boiling Point Measurement for physical verification
Documentation Provided
With every batch, we supply full documentation to support your compliance and quality checks:
- Certificate of Analysis (CoA)
- Safety Data Sheet (SDS)
- Batch Manufacturing Record (BMR)
- Material Safety Certificate (if required)
Custom Specifications
We understand different applications may require tailored grades. Gotrays provides:
- Customized purity levels (up to 99.9%)
- Specific impurity limits
- Packaging options aligned to your needs
- Analytical data as per customer-requested methods
If you need a 2-Chlorobenzonitrile grade for pharmaceuticals, agrochemicals, or specialized research, our technical team can create the right solution for you.
Applications & Uses of 2-Chlorobenzonitrile
Role as an Intermediate
2-Chlorobenzonitrile is widely valued as a key intermediate in organic synthesis. It’s a starting block for making more complex molecules, especially where a nitrile and chloro group positioned ortho to each other are needed. This makes it essential for developing various industrial chemicals.
Pharmaceuticals
In the pharmaceutical industry, 2-Chlorobenzonitrile plays a crucial part as a building block for active pharmaceutical ingredients (APIs). Its structure helps in synthesizing drug candidates and intermediates due to its versatility and reactive sites, especially in producing compounds targeting inflammation, infection, and neurological conditions.
Agrochemicals
For agrochemical manufacturing, it’s used to create herbicides, fungicides, and insecticides. Its role as an intermediate allows chemists to tailor molecules for better efficacy and environmental safety, making it a go-to compound in agrochemical R&D.
Specialty & Fine Chemicals
In specialty chemicals, 2-Chlorobenzonitrile contributes to creating dyes, pigments, and other fine chemicals. Its chemical properties enable fine-tuning of the end product’s performance, appealing to sectors requiring high purity and specific functionality.
Research & Development
Research labs rely on 2-Chlorobenzonitrile for exploring new synthetic routes and chemical transformations. It’s a preferred choice for testing reaction mechanisms, optimizing processes, and developing novel compounds in both academic and industrial R&D settings.
By serving multiple industries—from pharmaceuticals to agrochemicals and fine chemicals—2-Chlorobenzonitrile is a versatile compound bridging innovation and practical application worldwide.
Synthetic Routes & Reactivity of 2-Chlorobenzonitrile
General Synthetic Routes
2-Chlorobenzonitrile is mainly synthesized through:
- Chlorination of benzonitrile: Direct electrophilic substitution introduces chlorine at the ortho position.
- Sandmeyer reaction: Starting from 2-aminobenzonitrile, conversion to diazonium salt followed by replacement with chlorine.
- Nucleophilic aromatic substitution: In some cases, chlorine is introduced via displacement on activated precursors.
These routes offer flexibility depending on the desired purity and scale.
Typical Reactions & Transformations
2-Chlorobenzonitrile is a versatile intermediate, easily undergoing:
| Reaction Type | Description | Application |
|---|---|---|
| Nucleophilic substitution | Replaces chlorine with nucleophiles for diverse derivatives | Fine chemicals & pharmaceuticals |
| Reduction | Converts nitrile to amine groups | Building blocks in agrochemical synthesis |
| Hydrolysis | Turns nitrile into carboxylic acids | Specialty chemical production |
| Cross-coupling | Forms C–C bonds using Pd-catalysts | Advanced intermediates in R&D |
Advantages in Process Chemistry
- High selectivity: Chlorination at the ortho-position simplifies downstream reactions.
- Good stability: Offers safe handling and storage during processing.
- Scalability: Routes are effective for both lab-scale and industrial production.
- Diverse reactivity: Enables tailored synthesis of pharmaceuticals, agrochemicals, and fine chemicals.
By choosing the right synthetic pathway, manufacturers can optimize yield, reduce waste, and improve cost-efficiency—key factors for global supply reliability.
Safety, Handling & Regulatory Information for 2-Chlorobenzonitrile
GHS Classification & Labeling
2-Chlorobenzonitrile is classified under GHS as harmful if swallowed or inhaled. It carries hazard pictograms for irritants and health hazards. Proper labeling includes warnings about skin and eye irritation and respiratory protection. Always check the Safety Data Sheet (SDS) before use.
Toxicological Information (Overview)
Exposure to 2-chlorobenzonitrile can cause irritation to the skin, eyes, and respiratory tract. Prolonged or high-level contact may affect health, so avoid direct contact and inhalation. Use appropriate PPE such as gloves and goggles during handling.
Safe Handling Guidelines
- Handle in a well-ventilated area or under a fume hood.
- Avoid breathing dust or vapors.
- Wear protective gloves, safety goggles, and lab coats.
- Wash hands thoroughly after use.
- Keep away from incompatible substances like strong oxidizers.
Storage & Stability
Store 2-chlorobenzonitrile in a cool, dry place away from direct sunlight and heat sources. Keep containers tightly closed and sealed to maintain quality and prevent contamination. It is stable under normal warehouse conditions but keep away from moisture and strong acids.
Transport & Regulatory Compliance
2-Chlorobenzonitrile is subject to transportation regulations for hazardous chemicals, including proper packaging and labeling as per international standards (e.g., ADR, IATA, IMDG). Our product is REACH compliant, ensuring it meets global chemical safety standards. Always comply with local and international laws when shipping or receiving this chemical.
For any questions on handling or regulations, contact us for updated Safety Data Sheets and guidance tailored to your region.
Packaging, Supply Forms & Logistics of 2-Chlorobenzonitrile
Standard Packaging Options
We offer 2-Chlorobenzonitrile in various standard packages to suit your needs:
- 1 kg bottles (glass or HDPE)
- 5 kg drums (HDPE or metal)
- 25 kg drums (for bulk orders)
- Custom packaging also available on request
Packaging Materials
Our packaging materials are carefully chosen to ensure optimum product safety:
| Packaging Type | Material | Purpose |
|—————-|—————-|—————————–|
| Bottles | Glass / HDPE | Small-scale use, easy access |
| Drums | HDPE / Metal | Bulk storage, chemical stability |
Supply Capacity & Lead Time
- Regular stock maintained to fulfill urgent orders
- Supply capacity: Up to several tons per month globally
- Lead time: Typically 1-2 weeks for standard packages, faster on request
Storage & Transportation Logistics
- Store in a cool, dry, and well-ventilated area away from incompatible chemicals
- Transport under standard chemical shipping protocols, ensuring packaging integrity
- Fully compliant with international transport regulations (IMDG, IATA, ADR)
Customized Packaging Solutions
We accommodate special requirements such as:
- Specific container sizes
- Labeling and documentation tailored to your region’s regulations
- Enhanced packaging for sensitive shipping conditions
For flexible and reliable delivery of 2-Chlorobenzonitrile, our logistics team supports smooth supply, helping you plan ahead with confidence.
Quality Management & Certifications (Gotrays)
At Gotrays, quality is our top priority when supplying 2-Chlorobenzonitrile. Our strict quality system ensures every batch meets high standards, guaranteeing you receive consistently high-purity 2-Chlorobenzonitrile suited for critical applications.
Gotrays Quality System
- Thorough quality checks at every production stage
- Compliance with international standards like REACH and GHS
- Continuous improvement to maintain purity and consistency
Manufacturing & QC Controls
- State-of-the-art facilities with advanced process controls
- Rigorous in-house testing including chromatography and spectroscopy
- Batch-to-batch uniformity ensuring reliable performance
Regulatory & Compliance Support
- Complete documentation including safety data sheets (SDS) and certificates of analysis (CoA)
- Support for global regulatory requirements for pharmaceuticals, agrochemicals, and fine chemicals
- Assistance with registration and compliance for smooth import/export
Partnering with Gotrays means you get 2-Chlorobenzonitrile backed by solid quality assurance and dedicated regulatory support—key for your supply chain confidence.
Customization & Technical Support for 2-Chlorobenzonitrile
At Gotrays, we understand that every project is unique. That’s why we offer custom synthesis and process optimization services tailored to your specific needs with 2-Chlorobenzonitrile.
What We Offer:
| Service | Description |
|---|---|
| Custom Synthesis | Modify purity, particle size, or physical form to fit your process. |
| Process Optimization | Improve yield, reduce waste, and lower production costs. |
| Technical Consultation | Expert advice from our chemists on compound handling and applications. |
| Collaborative Projects | Work jointly on R&D or scale-up projects to fast-track your development. |
Our team is ready to support your goals, whether it’s scaling up for pharma, agrochemical manufacturing, or specialty chemical applications.
Reach out to Gotrays for dedicated technical backup and tailored solutions that help you get the most from your 2-Chlorobenzonitrile supply.
Ordering Information & Commercial Terms for 2-Chlorobenzonitrile
How to Place an Order
Ordering 2-Chlorobenzonitrile from Gotrays is simple. You can contact our sales team directly via email, phone, or through our website inquiry form. Provide details like your required quantity, purity level, and delivery location. We’ll respond quickly with availability and next steps.
Minimum Order Quantity (MOQ)
Our standard MOQ is flexible, starting from as low as 1 kg, depending on your needs. We accommodate both small-scale R&D orders and large commercial volumes, ensuring you only buy what fits your project.
Pricing & Quotations
Pricing for 2-Chlorobenzonitrile is competitive and scalable based on quantity and custom specifications. Request a detailed quotation by sharing your order specifics. We offer transparent pricing with no hidden fees, including cost breakdowns for bulk and repeat orders.
Sample Policy
Samples are available to help you test the quality before ordering in bulk. Contact us for sample requests—usually free or low-cost depending on quantity and location. This supports confident decision-making when sourcing 2-Chlorobenzonitrile.
Payment & Incoterms
We accept multiple payment methods including bank transfers, credit terms for approved customers, and internationally recognized payment options. Our shipments follow Incoterms (such as FOB, CIF) tailored to your preferred delivery terms. We’ll clearly outline payment terms during the quotation and ordering process to avoid confusion.
For a smooth ordering experience tailored to your global sourcing needs, Gotrays is here to assist you every step of the way.
Frequently Asked Questions (FAQ) about 2-Chlorobenzonitrile
Product & Specification
| Question | Answer |
|---|---|
| What is the purity of 2-Chlorobenzonitrile offered? | We provide high purity grades, typically 98%+ for most applications. |
| Is the product REACH compliant? | Yes, our 2-Chlorobenzonitrile meets REACH compliance standards. |
| What are the common forms supplied? | Supplied as powder or crystal, depending on customer needs. |
Safety & Regulatory
| Question | Answer |
|---|---|
| Is there a Safety Data Sheet (SDS) available? | Absolutely. We provide an updated 2-Chlorobenzonitrile safety data sheet with every order. |
| What precautions are needed when handling? | Use gloves, goggles, and work in a ventilated area to avoid inhalation or skin contact. |
| How is the product classified under GHS? | It is classified as hazardous with specific labeling for irritants and environmental risks. |
Logistics & Supply
| Question | Answer |
|---|---|
| What is the typical lead time for orders? | Standard lead time is 2-3 weeks, depending on order size and destination. |
| Are there options for customized packing? | Yes, we offer tailored packaging solutions to suit storage and transport needs. |
| What shipping methods are used? | We ship by air, sea, or land ensuring regulatory compliance for hazardous materials. |
Custom Requirements
| Question | Answer |
|---|---|
| Can you provide custom synthesis of 2-Chlorobenzonitrile? | Yes, we offer custom synthesis and process optimization on request. |
| Is technical support available for special projects? | Our expert team is ready to assist with technical consultation and project collaboration. |
| Can specifications be modified per customer needs? | Custom specifications are available with prior discussion and agreement. |
If you have more questions about our 2-Chlorobenzonitrile or need help with orders, feel free to contact us anytime.
Why Choose Gotrays for 2-Chlorobenzonitrile?
When you need 2-Chlorobenzonitrile, Gotrays stands out as your trusted supplier. Here’s why working with us makes a difference:
| Feature | What It Means for You |
|---|---|
| Supplier Reliability | Consistent supply, on-time delivery, and global reach keep your projects on track. |
| Technical & Service Advantages | Expert support for product selection, custom synthesis, and troubleshooting. We help optimize your process. |
| Competitive Edge | High-purity 2-Chlorobenzonitrile at competitive prices, tailored to your specifications. Flexible MOQ and quick turnaround. |
| Sustainability & Responsibility | Commitment to eco-friendly practices and fully compliant with REACH and safety standards. Your responsible choice. |
We understand global market demands and cater to industries like pharmaceuticals, agrochemicals, and fine chemicals with a product you can rely on. Choose Gotrays for quality and service that boost your success with 2-Chlorobenzonitrile.
Contact Gotrays
Multiple Contact Channels
Getting in touch with Gotrays is simple. You can reach us via email, phone, or live chat on our website. Our dedicated team is ready to assist you with any inquiries about 2-Chlorobenzonitrile or other chemical products.
Global Reach
No matter where you are—Asia, Europe, or the Americas—Gotrays supports your supply needs with reliable shipping and local customer service. We understand the importance of timely delivery and regulatory compliance worldwide.
Ready to Support Your Project?
Whether you need high-purity 2-Chlorobenzonitrile, custom packaging, or technical consultation, we’re here to help. Contact Gotrays today for a quote, samples, or detailed product information. Let’s work together to meet your chemical sourcing needs efficiently.
Reviews
There are no reviews yet.