Sodium Chlorodifluoroacetate CAS 2837 90 3 High Purity 98 Gotrays

Product Overview: High-Purity Sodium Chlorodifluoroacetate

We specialize in the manufacturing and global supply of Sodium chlorodifluoroacetate (CAS 1895-39-2), a critical organofluorine building block for advanced organic synthesis. As a stable, non-hygroscopic solid, this compound serves as a superior difluorocarbene precursor, enabling the generation of reactive $:CF_2$ species under mild, neutral thermal conditions. Unlike traditional reagents that require harsh bases or high pressures, our product facilitates controlled difluoromethylation and cyclopropanation with enhanced safety and ease of handling.

At Gotrays, we distinguish our Chlorodifluoroacetic acid sodium salt through rigorous process control, specifically targeting low moisture content and superior solubility. Our production standards ensure that the material dissolves rapidly in organic solvents like diglyme or DMF, preventing side reactions often caused by water contamination. Whether used for fluorinated pharmaceutical intermediates or agrochemical development, our Sodium 2-chloro-2,2-difluoroacetate delivers the consistency required for high-yield industrial applications.

Technical Specifications of Sodium Chlorodifluoroacetate

When you are sourcing Sodium chlorodifluoroacetate CAS 2837-90-3, consistency is the most important factor. We know that for your synthesis to work, the reagents need to be spot on every time. Below you will find the detailed C2ClF2NaO2 chemical properties that define our product quality.

We maintain strict control over moisture and purity levels to ensure this high purity chlorodifluoroacetate performs reliably in your lab or pilot plant.

Key Chemical Data

Property	Specification
Appearance	White to off-white crystalline powder
Assay (Purity)	≥ 98.0%
Molecular Formula	C2ClF2NaO2
Molecular Weight	152.48 g/mol
Melting Point	196-198°C (Decomposes)
Solubility	Soluble in water, methanol, and polar organic solvents
Moisture Content	≤ 0.5%
MDL Number	MFCD00004183
CAS Number	2837-90-3

Note: The low moisture content (≤ 0.5%) is critical for maintaining stability, making this an ideal difluorocarbene precursor for sensitive reactions.

Key Applications & Synthesis Utility

As a specialized Sodium chlorodifluoroacetate supplier, we understand that the value of this compound lies in its versatility as a reagent in organic synthesis. We provide high purity chlorodifluoroacetate that serves as a critical building block for advanced chemical manufacturing, particularly where precise fluorination is required.

Difluorocarbene Generation

The primary utility of Sodium chlorodifluoroacetate is its role as a reliable difluorocarbene precursor. Under neutral or mild conditions, it decomposes to generate difluorocarbene ($:CF_2$), avoiding the harsh environments required by other reagents. This makes it the preferred choice for:

• Difluorocyclopropanation: Efficiently converting alkenes into difluorocyclopropanes.
• Difluoromethylation: Introducing the $CF_2H$ group into nucleophiles, acting as a potent difluoromethylation reagent.

Pharmaceutical Intermediates

In the pharmaceutical industry, incorporating fluorine atoms often enhances the metabolic stability and lipophilicity of drug candidates. Our product is extensively used to synthesize fluorinated pharmaceutical intermediates. By using Sodium 2-chloro-2,2-difluoroacetate, chemists can modify bioactive molecules to improve their efficacy and duration of action in the body.

Agrochemical Synthesis

Beyond healthcare, this compound is vital for the agricultural sector. It functions as a key raw material in developing next-generation herbicides and pesticides. The stability provided by the fluorine groups helps create agrochemicals that are more effective at lower dosages.

Wittig-type Reaction Reagents

For complex organic transformations, Sodium chlorodifluoroacetate is utilized in Wittig-type reaction reagents. It facilitates the conversion of carbonyl compounds into gem-difluoroolefins, a structural motif increasingly sought after in both material science and medicinal chemistry. We ensure our organofluorine building blocks meet the rigorous purity standards required for these sensitive catalytic cycles.

Sodium Chlorodifluoroacetate MSDS & Safety Guidelines

We prioritize safety and compliance in every shipment. While Sodium chlorodifluoroacetate is a stable reagent, proper handling is essential to maintain the integrity of these industrial grade fluorochemicals and ensure operator safety.

Storage Best Practices

To prevent degradation and ensure consistent performance in synthesis, we recommend strict environmental controls:

• Environment: Store in a cool, dry, and well-ventilated area.
• Sealing: Keep containers tightly closed at all times to avoid moisture absorption.
• Segregation: Store away from strong oxidizing agents and food materials.

Safety Precautions (PPE)

According to the Sodium chlorodifluoroacetate MSDS, operators should strictly adhere to standard laboratory hygiene practices to minimize exposure risks.

• Protective Gear: Always wear chemical-resistant gloves, safety goggles, and a lab coat. Use a dust mask if ventilation is poor.
• Hazard Statements:
  • H315: Causes skin irritation.
  • H319: Causes serious eye irritation.
  • H335: May cause respiratory irritation.

Transport Information

This product is generally classified as non-hazardous for transport, which simplifies logistics for our global partners. However, we ensure all packaging meets international shipping standards to prevent accidental spills or exposure during transit. Always refer to the full Safety Data Sheet (SDS) provided with your order for detailed regulatory information.

Packaging and Global Logistics for Sodium Chlorodifluoroacetate

We understand that secure packaging is critical to maintaining the stability of C2ClF2NaO2 chemical properties during transit. As a reliable bulk sodium chlorodifluoroacetate supplier, we offer flexible packaging solutions designed to protect the product from moisture and physical damage while meeting the specific needs of your production line.

Standard and Custom Packaging Options

Whether you are conducting initial R&D or moving to pilot plant production, we scale our packaging to fit your requirements:

• Lab Scale: Available in 25g, 100g, and 500g units, typically packed in fluorinated bottles or aluminum foil bags to ensure freshness for testing.
• Commercial Scale: For industrial grade fluorochemicals, we utilize 25kg Fiber Drums lined with double-layer polyethylene (PE) bags. This ensures the material remains dry and free from contamination.
• Custom Solutions: We can adjust pack sizes to match your specific batch requirements, minimizing waste and exposure during your manufacturing process.

Global Shipping and Compliance

Our logistics team is experienced in handling the international distribution of organofluorine building blocks. We ensure seamless delivery to Europe, North America, and Asia with full regulatory compliance.

• Regulatory Adherence: All shipments are compliant with REACH regulations and local import standards.
• Documentation: We provide complete shipping documents to expedite customs clearance.
• Safety: Although classified as non-hazardous for transport, we strictly adhere to safety protocols to ensure your order arrives in perfect condition.

Quality Control and Certification for Sodium Chlorodifluoroacetate

We prioritize consistency and transparency in our supply chain. Before any shipment leaves our facility, our Sodium chlorodifluoroacetate undergoes rigorous testing to ensure it meets the strict demands of pharmaceutical and agrochemical production. We use advanced analytical methods to guarantee you receive high purity chlorodifluoroacetate suitable for sensitive organic synthesis.

Our quality assurance process includes:

• Purity Verification: We validate composition using GC (Gas Chromatography) and NMR analysis to confirm the specific C2ClF2NaO2 chemical properties and ensure the assay meets or exceeds 98.0%.
• Comprehensive Documentation: Every order is accompanied by a Certificate of Analysis (COA) and a Sodium chlorodifluoroacetate MSDS (Material Safety Data Sheet) to support your regulatory compliance and safety protocols.
• ISO Compliance: Our manufacturing operations adhere to ISO quality management systems, ensuring reliable scalability and traceability from lab samples to commercial bulk lots.

Frequently Asked Questions (FAQ)

Advantages Over Other Difluorocarbene Reagents

We often get asked why Sodium chlorodifluoroacetate is preferred over other sources like chlorodifluoromethane or TFDA. The main advantage is safety and ease of handling. Unlike gaseous reagents that require high-pressure equipment, our product is a stable, solid difluorocarbene precursor.

• Milder Conditions: It generates difluorocarbene under neutral or mild conditions, avoiding the need for harsh bases that might damage sensitive substrates.
• Higher Selectivity: It offers better control during difluorocyclopropanation and difluoromethylation reactions.
• Operational Safety: As a solid chlorodifluoroacetic acid sodium salt, it eliminates the hazards associated with handling toxic gases in the lab.

Addressing Hygroscopic Nature and Sealing Protocols

While we manufacture Sodium chlorodifluoroacetate to be a free-flowing powder with low moisture content, sodium salts can naturally be hygroscopic if left exposed. To ensure you receive high purity chlorodifluoroacetate, we implement strict sealing protocols.

• Moisture Control: We maintain a moisture content of ≤ 0.5% during production.
• Packaging: Our containers are hermetically sealed immediately after QC testing to prevent water absorption.
• Storage Advice: Always re-seal the container tightly after use and store it in a cool, dry place as per the Sodium chlorodifluoroacetate MSDS.

Availability of Bulk Orders for Pilot Plant Production

Yes, we are a fully equipped bulk sodium chlorodifluoroacetate supplier capable of supporting your project from the bench to the factory floor. We understand that scaling up requires consistent quality.

• Scalability: We supply quantities ranging from gram-scale samples for R&D to metric tons for industrial grade fluorochemicals.
• Pilot Support: We provide the necessary technical data and organofluorine building blocks to help you validate your process in pilot plants before full commercial rollout.
• Supply Chain: Our global logistics network ensures timely delivery of fluorinated pharmaceutical intermediates to facilities in Europe, North America, and Asia.