High Purity Pyrazole CAS 288131 Supplier for Pharma Use

Product Snapshot: Pyrazole (CAS 288-13-1)

As a dedicated manufacturer of heterocyclic compounds, we supply high-purity Pyrazole (1,2-Diazole) designed for rigorous industrial and research applications. By controlling the synthesis process from raw material to final packaging, we eliminate the variability often found in the spot market. Our direct manufacturing model ensures you receive a consistent C3H4N2 chemical structure optimized for use as a core pharmaceutical intermediate or agrochemical building block.

Essential Chemical Identifiers

Property	Specification
Product Name	Pyrazole (1H-Pyrazole)
CAS Number	288-13-1
Molecular Formula	$C_3H_4N_2$
Molecular Weight	68.08 g/mol
Synonyms	1,2-Diazole, Monazole

Stock Availability & Grade Options

We understand that procurement speed is critical. We maintain strategic stock levels to ensure rapid deployment for both pilot projects and full-scale manufacturing.

• Industrial Grade: Optimized for cost-effective production of agrochemicals and specialized dyes.
• Pharma Grade: High-purity specifications (≥99.0%) with strict impurity control for sensitive organic synthesis reagents.
• Supply Capacity: Flexible volume options ranging from R&D samples to bulk FCL shipments.

Technical Specifications & Chemical Properties

We understand that consistent chemical behavior is non-negotiable for your production line. Our Pyrazole (CAS 288-13-1) is manufactured to meet rigorous physical and chemical standards, ensuring it functions reliably as a core 1,2-Diazole building block in your synthesis.

Physical Appearance & Structure

We supply High-purity Pyrazole as a stable, white to off-white crystalline powder or flake. Its C3H4N2 Chemical Structure features a five-membered ring with two adjacent nitrogen atoms, making it a versatile organic synthesis reagent for complex formulations.

Purity Metrics & Solubility

To guarantee performance in sensitive applications, we validate every batch using GC/HPLC standards. We maintain strict control over moisture and impurities to prevent side reactions during downstream processing.

• Purity Grades: Available in standard ≥ 98.0% and premium ≥ 99.0% for specialized pharmaceutical use.
• Solubility: Excellent solubility in water, ethanol, and ether, facilitating easy integration into various solvent systems.

Key Technical Data

Property	Specification
Chemical Name	Pyrazole (1H-Pyrazole)
CAS Number	288-13-1
Molecular Formula	$C_3H_4N_2$
Molecular Weight	68.08 g/mol
Melting Point	67°C – 70°C
Boiling Point	186°C – 188°C
Appearance	White to off-white crystalline powder

Note: Detailed Certificate of Analysis (COA) and MSDS are available for specific batch data verification.

Key Applications in Pharmaceutical & Agrochemical Synthesis

Our Pyrazole (CAS 288-13-1) serves as a fundamental building block across multiple high-value industries. We understand that for our global clients, the reactivity and stability of the 1,2-Diazole ring are critical for successful downstream synthesis.

Role as a Core Pharmaceutical Intermediate

In the pharmaceutical sector, Pyrazole is indispensable. It acts as a primary Celecoxib intermediate, essential for the production of specific NSAIDs (Non-Steroidal Anti-Inflammatory Drugs). The unique structure allows for the development of potent analgesic and anti-inflammatory medications. We ensure our supply meets the rigorous purity standards required for these sensitive pharmaceutical intermediates.

Agrochemical Building Blocks

Beyond medicine, we supply the agricultural industry with reliable agrochemical building blocks. Pyrazole derivatives are key components in the synthesis of advanced crop protection agents, including:

• Fungicides: To control fungal pathogens in large-scale farming.
• Insecticides: For effective pest management solutions.
• Herbicides: For targeted weed control formulations.

Usage in Dye Synthesis & Energetic Materials

While pharma and agro are our biggest volume movers, we also support niche industrial applications. The compound is utilized in the creation of specialized industrial dyes and, due to its nitrogen-rich composition, plays a role in the research and development of energetic materials.

Why Pyrazole is the Preferred Nitrogen-Containing Heterocycle

Chemists prefer Pyrazole because of its balanced reactivity. As a nitrogen-containing heterocycle, it offers excellent thermal stability and versatility in substitution reactions. This makes it the go-to scaffold for designing complex bioactive molecules compared to other heterocyclic options.

Quality Assurance & Regulatory Compliance

We understand that consistency is the most critical factor when sourcing chemical raw materials. Our quality control system is designed to eliminate variability between batches, ensuring that the Pyrazole (CAS 288-13-1) you receive performs exactly as expected in your synthesis processes.

Rigorous Testing Protocols

To guarantee the integrity of our high-purity Pyrazole, we employ a multi-step analysis process before any product leaves our facility. We don’t just rely on basic checks; we validate chemical identity and purity using advanced instrumentation.

• GC & HPLC Analysis: Used to confirm purity levels (typically ≥ 99.0%) and detect trace organic impurities.
• NMR Spectroscopy: Verifies the molecular structure and ensures the correct isomer profile.
• Moisture Analysis: Strictly monitored to prevent degradation, as Pyrazole can be sensitive to environmental conditions.

Comprehensive Documentation & Transparency

Global manufacturing requires complete traceability. We provide a full suite of technical documents to support your regulatory filings and internal audits:

• Certificate of Analysis (COA): Detailed batch-specific data.
• MSDS/SDS: Updated safety data sheets compliant with international safety standards.
• Route of Synthesis (ROS): Available upon request for clients requiring deep supply chain visibility.

Managing Impurity Profiles & Standards

For clients using 1,2-Diazole as a pharmaceutical intermediate, controlling the impurity profile is non-negotiable. We strictly manage side-reaction byproducts to ensure our material is suitable for sensitive applications. Our operations align with ISO standards and we actively monitor REACH compliance requirements to facilitate smooth export to European and global markets.

Packaging, Storage, and Logistics

We understand that product integrity during transit is just as critical as the synthesis process itself. As a dedicated chemical raw material supplier, we have optimized our supply chain to ensure your Pyrazole (CAS 288-13-1) arrives in the exact same high-purity condition it left our facility. Whether you are a research lab or a large-scale manufacturer, our logistics adhere to strict safety standards.

Standard Packaging Options

We offer flexible packaging solutions tailored to your consumption rate. We use high-quality materials to protect the chemical integrity of the 1,2-Diazole structure during transport.

Order Scale	Packaging Type	Protection Features
Lab / R&D	1kg Aluminum Foil Bag	Light-proof, moisture-sealed
Pilot / Bulk	25kg Fiber Drum	Double PE inner liners, impact-resistant

Storage and Hygroscopic Control

Since Pyrazole can be hygroscopic, preventing moisture absorption is our top priority. Our drums feature double polyethylene liners to create a robust barrier against humidity. Upon receipt, we recommend storing the inventory in a cool, dry, and well-ventilated area away from incompatible materials. Proper storage ensures the material remains free-flowing and reactive for your synthesis needs.

Global Shipping & Lead Times

We handle the complex logistics so you don’t have to. Our logistics team is fully trained in IATA and IMDG regulations, ensuring safe and compliant transport for hazardous materials via air or sea.

• Sample Requests: Typically dispatched within 24-48 hours for rapid validation.
• Bulk FCL: Streamlined processing for Full Container Loads to minimize downtime at your plant.
• Documentation: We provide complete tracking and safety documentation (SDS) with every shipment.

Custom Synthesis & Derivative Capabilities

We understand that standard catalog items do not always fit every project requirement. Beyond supplying high-purity 1H-Pyrazole, our facility is equipped to handle complex custom chemical synthesis to modify the pyrazole ligand structure for specialized industrial and pharmaceutical applications.

Modifying the Pyrazole Ring

Our R&D team excels at functionalizing the C3H4N2 chemical structure to create specific intermediates. We frequently produce derivatives like 3,5-Dimethylpyrazole and other substituted nitrogen-containing heterocycles. Whether you require specific alkylation or unique substitutions on the ring, we tailor the molecule to your exact specifications.

Scalability: From R&D to Mass Production

We support your product lifecycle at every stage, ensuring a consistent supply chain as you grow:

• Lab Scale: Gram-level synthesis for initial testing and validation.
• Pilot Batch: Kilogram quantities for process optimization.
• Commercial Supply: Metric tons delivered globally for industrial manufacturing.

Collaborative Formulation Support

We act as more than just a heterocyclic compounds supplier; we are your technical partner. Our team assists with reaction pathway optimization and stability testing, ensuring our organic synthesis reagents integrate seamlessly into your proprietary formulas.

Common Questions About Our Pyrazole Supply (FAQs)

What specific purity grades do you offer for pharma applications?

We primarily supply High-Purity Grade Pyrazole tailored for critical applications. For pharmaceutical intermediates, we recommend our ≥ 99.0% purity specification to ensure the lowest possible impurity profile during drug synthesis. We also offer a standard ≥ 98.0% grade for general industrial and agrochemical use.

Can you provide a sample for validation before bulk purchase?

Yes. We know that verifying chemical quality is the first step in establishing a supply partnership. We provide pre-shipment samples so your QC team can test the chemical structure and purity metrics against your specific standards before you commit to a commercial order.

How do you handle moisture control during shipping?

To prevent degradation, we use robust packaging designed for international logistics. Our Pyrazole is packed in fiber drums with double polyethylene liners, which creates an effective barrier against humidity. This ensures the material remains dry and free-flowing upon arrival.

What is the shelf life of your Pyrazole under standard conditions?

When stored in its original sealed packaging in a cool, dry, and well-ventilated area, our Pyrazole maintains stability for two years. We include a Certificate of Analysis (COA) with every shipment detailing the manufacturing date and recommended re-test date.

Do you offer custom substitution on the Pyrazole ligand structure?

Absolutely. Beyond standard CAS 288-13-1, our expertise in custom chemical synthesis allows us to modify the ring structure. Whether you need specific pyrazole ligands or alkyl-substituted derivatives, our R&D team can support your project from lab-scale trials to full production.